In [[1529]] he visited [[Rome]] and studied the works of [[Raffaello Santi|Raphael]] and others of the Roman [[High Renaissance]]. Vasari's own [[Mannerist]] paintings were more admired in his lifetime than afterwards. He was consistently employed by patrons in the [[Medici family]] in [[Florence]] and Rome, and he worked in [[Naples]], Arezzo and other places. Many of his pictures still exist, the most important being the wall and ceiling paintings in the great Sala di Cosimo I of the [[Palazzo Vecchio]] in Florence, where he and his assistants were at work from 1555, and his uncompleted [[fresco]]es inside the vast [[cupola]] of the [[Santa Maria del Fiore|Duomo]], completed by [[Federico Zuccari]] and with the help of [[Giovanni Balducci]]. He also helped organize the decoration of the [[Studiolo of Francesco I (Palazzo Vecchio)|Studiolo]], now reassembled in the Palazzo Vecchio. He was essentially the "Dick Clark" of the Renaissance, a leader in the art world, although not so much as a renowned artist but as a director of artistic productions.
[[Image:The Mutiliation of Uranus by Saturn.jpg|thumb|300px|''The Castration of Uranus'': fresco by Vasari & [[Cristofano Gherardi]] (c. 1560, Sala di Cosimo I, [[Palazzo Vecchio]], Florence).]]
Asในฐานะสถาปนิก anวาซารีประสบความสำเร็จมากกว่าในฐานะจิตรกร architect,Vasariทางเดิน was perhaps more successful than as a painter. The [[(loggia]]) ofระหว่างปราสาท theอูฟิซี [[Uffizi|(Palazzo degli Uffizi]]) byมีการนำสายตาของผู้เดิน the[[Arno]]ไปสู่ปราสาทอีกด้าน opens up the vista at the far end of its long narrow courtyard, a unique piece ofเป็นงานออกแบบเมือง (urban planning that functions as a public piazza, and which, if considing it as a short street, is the unique Renaissance street with a unified architectural treatment.design)ที่สำคัญมากของยุคนั้น In Florence Vasari also built the long passage connecting the Uffizi with the [[Pitti Palace]], through arcading across the [[Ponte Vecchio]], now called [[Vasari Corridor]] after him. He also renovated the fine medieval [[church]]es of [[Santa Maria Novella]] and [[Basilica di Santa Croce, Florence|Santa Croce]], from both of which he removed the original [[rood screen]] and loft, and remodelled the retro-[[choir]] in the Mannerist taste of his time.
In Rome, Vasari worked with [[Giacomo Barozzi da Vignola]] and [[Bartolomeo Ammanati]] at [[Pope Julius III]]'s [[Villa Giulia]].