แม่แบบ:โครงสร้างปฐมภูมิของโปรตีน

โครงสร้างปฐมภูมิของโปรตีนและการดัดแปลงโมเลกุลหลังการแปลรหัส

ทั่วไป

Single specific AAs

Serine/Threonine	Phosphorylation Dephosphorylation Glycosylation O-GlcNAc ADP-ribosylation Methylidene-imidazolone (MIO) formation
Tyrosine	Phosphorylation Dephosphorylation ADP-ribosylation Sulfation Porphyrin ring linkage Adenylylation Flavin linkage Topaquinone (TPQ) formation Detyrosination
Cysteine	Palmitoylation Prenylation
Aspartate	Succinimide formation ADP-ribosylation
Glutamate	Carboxylation ADP-ribosylation Methylation Polyglutamylation Polyglycylation
Asparagine	Deamidation Glycosylation
Glutamine	Transglutamination
Lysine	Methylation Acetylation Acylation Adenylylation Hydroxylation Ubiquitination Sumoylation ADP-ribosylation Deamination Oxidative deamination to aldehyde O-glycosylation Imine formation Glycation Carbamylation Succinylation Lactylation Propionylation Butyrylation
Arginine	Citrullination Methylation ADP-ribosylation
Proline	Hydroxylation
Histidine	Diphthamide formation Adenylylation
Tryptophan	C-mannosylation

Crosslinks between two AAs

Cysteine–Cysteine	Disulfide bond ADP-ribosylation
Methionine–Hydroxylysine	Sulfilimine bond
Lysine–Tyrosylquinone	Lysine tyrosylquinone (LTQ) formation
Tryptophan–Tryptophylquinone	Tryptophan tryptophylquinone (TTQ) formation

Three consecutive AAs
(chromophore formation)

Serine–Tyrosine–Glycine	p-Hydroxybenzylidene-imidazolinone formation
Histidine–Tyrosine–Glycine	4-(p-hydroxybenzylidene)-5-imidazolinone formation

Crosslinks between four AAs

Allysine–Allysine–Allysine–Lysine	Desmosine

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